Archive for SkinFactor Cream

Naturally Anti-Aging Cream

Skin Factor: an anti-aging cream that naturally repairs, rejuvenates and brings back the lost radiance

SkinFactor offers amazing anti-aging and skin rejuvenating benefits. Side effects? A glowing, nourished and youthful skin.

The SkinFactor cream by Biotrends comes with two primary ingredients – Hexapeptide 3 and Epidermal Growth Factors (EGFs); along with glycerol and rose water.

All these skin-healthy components come together and work to reduce stress lines, reclaim lost moisture and heal damaged skin.

Result? A naturally glowing, revitalized and healthy looking skin without using any harsh chemicals and without any side-effects.

Hex 3 and EGFs are peptides – long chain amino acids – that are making great waves as superior anti-aging ingredients. Peptides signal cells to produce more collagen, repair damaged skin and fight wrinkles and fine lines. They do all that you could ask for to give your skin a new lease of life and make your skin more beautiful.

Epidermal Growth Factors are The ultimate skin rejuvenators

Epidermal growth factor or EGF as it is commonly called is basically a polypeptide – a chain of amino acids. EGFs are naturally occurring proteins known to stimulate cellular growth, healing and regeneration [1].

Growth factors were discovered in 1986 by two scientists, Stanley Cohen and Rita Levi-Motalcini, who received a Nobel Prize in Medicine for this breakthrough discovery. Their work gave revolutionary insights into the ways in which cells communicate with each other during growth, differentiation, repair and healing.

EGFs encourage cellular repair and wound healing in the skin – meaning it possess incredible rejuvenating and age-reversing potential, all tapped and unlocked in our unique SkinFactor cream. When we say skin damage or repair, it includes injury or damage due to sun exposure, pollution, free radicals, burns, surgery and ageing. Basically, it works with unhealthy, damaged skin that needs repair and regeneration.

The skin repair and rejuvenating benefits offered by EGFs shouldn’t be surprising. These growth factors are naturally present in the fibroblasts of our skin, which are the cells responsible for producing extracellular matrix and collagen. A body of randomized controlled clinical trials suggest that topical growth factors achieve similar outcomes as endogenous growth factors, and reduce the signs associated with skin ageing. A recent 2016 article reports that topical growth factors are able to help “due to their capacity to promote dermal fibroblast proliferation and to stimulate extracellular matrix formation” [2].

How EGFs function?

Epidermal growth factors support the skin’s natural regeneration and revitalization process

It all starts with the inflammation stage. Inflammation may sound obnoxious but it is an integral mechanism of how our body responds to any injury, damage or infection. During this stage, our body transitions into an aggressive repair and healing mode by initiating certain events, and the release of EGFs is one of them. EGFs kick start cascading bio-chemical pathways that initiate tissue repair and regeneration in damaged skin cells – by signalling other cells and chemicals to arrive at the site of injury – and leads to:

  • Increased production of collagen and other elastin fibres
  • Growth of new blood vessels to supply nutrient and oxygen rich blood at the site of repair
  • Extracellular matrix deposition and remodelling

What does it mean for your skin? Creams with growth factors help in repairing damaged skin fast, boost collagen formation for increased elasticity, reduces age spots and pigmentation, and improve the skin’s integrity.

What is Hexapeptide -3?

Hexapeptide -3: Prevents the formation of expression lines and wrinkles

Like EGFs, Hexapeptide -3 is also a polypeptide. It is a chain of 6 amino acids and a fragment of SNAP-25, a substrate of Botox. Evidence suggest that hexapeptide-3 can reduce wrinkles by 30%, and within an impressive time frame of only 30 days.

How Hex 3 works: Relaxes facial muscles

We all age with time. Fine lines and wrinkles are a part of this natural ageing process. However, some external factors – such as over exposure to sun, smoking, drinking, stress and an unhealthy lifestyle – can play a major role in making our skin to age faster. There is another factor that contributes big time to this process – repetitive facial expressions.

Expressions like smiling, squinting and frowning make the underlying muscles contract, resulting in folds or creases. When we are young, our skin is more elastic and it has the flexibility to easily spring back into its place. But an ageing skin is no longer this versatile and flexible. Repetitive contractions of the facial muscles eventually pave way for permanent grooves and creases on the face. Well, we are all familiar with these furrows. Call them frown lines, crow’s feet or laugh lines, in the end they are something that we all dread. So how Hex 3 can help?

Hex 3 works by relaxing the facial muscles. Basically, Hex 3 blocks the communication that travels from nerves to muscles asking the muscles to contract. How?

At the neuromuscular junction, a site where a nerve fibre meets a muscle fibre:

  • Nerve cells release certain neurotransmitters (Acetylcholine and others)
  • The released chemicals transmit signals that activate a muscle fibre to contract.
  • These neurotransmitters are secreted with the help of SNARE proteins
  • SNARE proteins help nerves to release the neurotransmitters through a process called exocytosis.

Hexapeptide 3 interferes with the working of SNARE protein complex (it mimics one the proteins in the complex) and disrupts their function. Result? Chemicals that signal the muscle to contract are blocked, muscles don’t contract – thus preventing the formation of expression lines or wrinkles.

SkinFactor also contains glycerol and rose water


Glycerol is great for skincare not for one but many reasons:

  • Acts as a highly effective moisturizer
  • Soothes dry, damaged skin
  • Keeps skin nourished and hydrated
  • Enables young skin cells to mature and develop properly

Pure rose water

Besides imparting a delightful fragrance of fresh roses, pure rose water has a lot of skin benefits to offer:

  • Has anti-inflammatory and antioxidant properties
  • Soothes and cools irritated skin
  • Maintains moisture as well as pH balance in the skin
  • Stops bacterial growth, helps in reducing acne and pimples
  • Improves skin tone

Why should you buy SkinFactor?

Because it is one factor missing in your challenge to maintain a healthy, nourished and glowing skin without any side effects at all!!

What makes SkinFactor a unique antiaging cream? Synergistic combination of Hexapeptide, Epidermal growth factors, glycerol and rose water – a rare blend in any skincare product!

  1. Hexapeptide 3 relaxes facial muscles – to avoid expression wrinkles
  2. EGFs stimulate skin regeneration and repair – for better healing against sun exposure and other damage inflicted to skin
  3. EGFs also boosts collagen production – for a firm, elastic and supple skin
  4. Glycerol and rose water helps in keeping skin hydrated, nourished and overall healthy.
  5. Results as effective as Botox application. The big difference?  No toxic side effects, easy application and affordable



  1. Barrientos S et al. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008 Sep-Oct; 16(5):585-601. doi: 10.1111/j.1524-475X.2008.00410.x.
  2. Frank Dreher. Topical Growth Factors for Skin Rejuvenation. Textbook of Aging Skin. Pp 1-12. April 2016.

The SkinFactor cream

The cream that signals the skin to repair and rejuvenate:

Here is what Biotrends tells us on the label, concerning its different components:

➡️ Epidermal Growth Factor (E.G.F.):

In clinical studies and use for the past 10 years, it is showed that it improves the texture and appearance of the skin.
Studies show that it works as it helps in the regeneration and repair of epidermal damage by stimulating the natural synthesis of hyaluronic acid, and by helping the skin to absorb nutrients.

➡️ Héxapeptide-3 :

It was shown as reducing the appearance of fine lines and wrinkles in the skin, helping to relax the stressed muscles that are responsible for those wrinkles.

➡️ Glycérol (not only a preservative):

It helps moisturise and soften the skin. In addition, research shows that glycerol helps skin cells to develop properly, allowing younger cells to migrate to deeper levels, and grow to maturity by becoming surface cells that produce lipids that protect the skin.

➡️  And they added Rose water for 2 reasons:

This improves the smell of the product of course, but especially the main reason are the well known benefits of rose water on the skin. The Rose water is used is 100% distilled roses. It gives a slight perfume that is released after application to the skin.

=> There are now many commercial products that contain either EGF (FCE) or hexapeptide 3, but none contains the two to act in synergy.
In addition, products that contain Epidermal Growth Factor, have only very small amounts, so small that they dare not specify this amount on the label.

Ti the contrary, each 30ml vial product SkinFactor contains 30mcg of EGF, 2.5 mg of Hexapeptide-3, and 5% glycerol, which are the ideal doses, not too low nor too high, corresponding to the natural capacity of absorption of the skin.

➡ Use / dosage:

BioTrends recommends to squeeze 3 or 4 times the cap in the palm of the hand, then lightly rub both hands, and then use your palms to apply the product on the skin of the face, neck and back of hands.

For local applications, press 1 or 2 times the product on the tip of the index and then apply it in circles on the desired location.

# From experience since I started using this gel for several months, I can say that the effects are seen in the second week, before the end of the first bottle, and after 2 months I had far less wrinkles and the most important ones were much less dramatic, and slumps are tightened!

➡ How to rejuvenate my skin, and stop harming it?

When we reach 35, 40, 50 or 60 years we all have the tendency to try to stop the degradation of our physical appearance.

By studying ageing we discovered that people follow a different biological rhythm, and age effects do not manifest in the same way, even when you take 2 twins.

Some people seem younger than their age, while for others it is the reverse, and sometimes difference between apparent age and biological age may be 10 or 15 years!

  • Myself, at age 40 years I seemed to have more than 50, with a dry and wrinkled skin, grey and dry hair like a much older person … until I took my first doses of Epitalon, and you know the rest …
    (To read my testimony rejuvenation go here

There are a variety of factors that come into play to regulate ageing and genetics is only one of these factors.

Examples of twins, who therefore have the same biological age and the exact same genetics, and yet the difference in appearance is obvious!

Regarding the skin it is obvious that genetics is not everything, personal habits have a huge role to play.

In the picture above it is clear that the right sister exposes herself to much more sun than the other, hence the brown spots covering almost the entire surface of her face, and thicker skin which therefore makes wrinkles much deeper.

  • Of course you can work on hair and makeup to look younger and have a vibrant air, but any closer look and we can see the real state of the skin:

  • Living outdoors is definitely essential for good health and for the joy of life, but attention to the effects on the skin:

We can see the thicker and dropping skin on the left twin, and all the brown spots that show a greater exposure to the sun, although their complexion shows that they both have naturally freckles.

  • A living food, full of fresh vegetables with lots of micro-nutrients and antioxidants is an essential factor for good health, but also for a beautiful skin.
    We know that the body needs vitamin C to produce collagen which constitute our skin but also our bones and other body tissues.

Fresh fruits and vegetables also allow optimal hydration of the skin by the pure water contained therein, and with their essential minerals for the retention of this water in the body and thus by the skin.

But despite a good diet we do not remain equal with the ageing of our skin.

Of course there are many products on the market to take care of the skin, but the evidence is clear that they do not work at all, and are only for commercial purposes, and not to actually repair and rejuvenate our skin.

At least until the arrival of the cream by BioTrends, because it contains the optimal amount to boost reparation and production of the skin.

BioTrends supplies cosmetic industries in several countries of the world, but they found that the manufacturers put only very small doses of these expensive and complicated molecules to manufacture in their products, and the results obtained by the buyers can therefore be only minimal.

That’s why BioTrends launched its own anti-wrinkle cream, the only one in the world that contains molecules that really work, especially in the quantities needed for powerful action.

As they say, try it and adopt it, because the results are seen and are impressive in most cases.

  • Sun exposure is certainly the worst trauma for our skin, as these pictures taken with a camera and special software show:

(English truck driver, who then drive on the left)

The author of this exclusive documentary for the BBC, which is a causal driver, with important difference between the two sides of his face:

The main factors that destroy collagen in the skin and oxide it, creating wrinkles, are:

  1. Sun exposure
  2. Smoking
  3. Lack of hydration
  4. Genetics
  5. Oxidant food

It is therefore the interaction of these different factors that determine the speed of ageing of the skin.

  • We saw above the effects of the sun, now let’s see those from smoking:

Tobacco is known to oxidise and destroy vitamin C, and thus blocking the formation of collagen …

Smoking is a major factor in the creation of wrinkles, for both sexes, and its association with wrinkles is even stronger than sun exposure!

In one of the scientific studies on the subject, smokers from 40 to 49 years were as wrinkled as their non-smoking counterpart of 60 to 69 years.

It means that smoking all your life, your skin is over aged by 20 years, even before reaching your 50 years.

  • And finally, to thank the author of this very informative video, here is her picture at the age of 46, compared with that of her mother when she was 43 years old. It is clear that a living food, not smoking and little sunshine retain the youthful appearance that we appreciate so much!

Her CONCLUSION is that we do not need creams if we take care of our diet and habits of our lives … so it’s up to you!

As for me I told her she would be even more beautiful and have a more youthful skin if she applied the messenger molecules that would signal it to renew and repair itself, such as those present in the anti-ageing cream offered by BioTrends, the forefront of modern research against human ageing factors.

So the choice is yours … but why not give a chance to BioTrends … and to your skin, by just trying this cream for 2 or 3 months, for an incredible rejuvenation, almost guaranteed!

Good health and long life to you!


➡ Find out how to register on BioTrends here if you haven’t already.