Firstly thank you for your registration, and thank you for your interest in your own well-being and your health and longevity.
Here is some essential information to fight against aging:
Epitalon stimulates and re-establish the production of melatonin, an essential factor to stay in good health !
Here is a short selection of studies already published :
This one concerns epitalon and melatonin that are able to correct reproduction cycles in rats :
– PMID: 23237594 : Melatonin and pineal gland peptides are able to correct the impairment of reproductive cycles in rats.
Arutjunyan A, Kozina L, Milyutina Y, Korenevsky A, Stepanov M, Arutyunov V.
Curring Aging Sci. 2012 Dec;5(3):178-85.
This one concerns molecular cellular mechanisms of melatonin synthesis by epitalon :
– PMID: 22816096 : Molecular cellular mechanisms of peptide regulation of melatonin synthesis in pinealocyte culture.
Khavinson VKh, Linkova NS, Kvetnoy IM, Kvetnaia TV, Polyakova VO, Korf HW.
Bull Exp Biol Med. 2012 Jun;153(2):255-8. English, Russian.
This one concerns the regulatory effect of epitalon on melatonin and cortisol production :
– PMID: 11550036 : Regulatory effect of Epithalon on production of melatonin and cortisol in old monkeys.
Goncharova ND, Khavinson BK, Lapin BA.
Bull Exp Biol Med. 2001 Apr;131(4):394-6.
This one concerns the effects of epitalon and melatonin on ageing of thyroid and hypophysis :
– PMID: 20405731 : Effect of preparations melatonin and epitalon on the age-related dynamics of thyrotrophic activity of the hypophysis and thyroid gland function in different light regimes.
Adv Gerontol. 2009;22(4):631-8. Russian.
This one concerns the effect of epitalon on melatonin production by the pineal gland :
– PMID: 12809170 : Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.
Djeridane Y, Khavinson VKh, Anisimov VN, Touitou Y.
J Endocrinol Invest. 2003 Mar;26(3):211-5.
This one concerns epitalon correcting neuroendocrine regulations in old monkeys :
– PMID: 11524632 : Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys.
Khavinson V, Goncharova N, Lapin B.
Neuro Endocrinol Lett. 2001 Aug;22(4):251-4.
This one concerns the influence of epitalon and melatonin on the number of leukocytes :
– PMID: 19432172 : The influence of melatonin and epithalon on blood leukocyte count and leukocyte alkaline phosphatase in rats under different lighting conditions during ontogenesis.
Uzenbaeva LB, Vinogradova IA, Golubeva AG, Niuppieva MG, Iliukha VA.
Adv Gerontol. 2008;21(3):394-401. Russian.
 Melatonin and Epitalon, studies on PubMedhttp://www.ncbi.nlm.nih.gov/pubmed/?term=melatonin+epitalon