Naturally Anti-Aging Cream

Skin Factor: an anti-aging cream that naturally repairs, rejuvenates and brings back the lost radiance

SkinFactor offers amazing anti-aging and skin rejuvenating benefits. Side effects? A glowing, nourished and youthful skin.

The SkinFactor cream by Biotrends comes with two primary ingredients – Hexapeptide 3 and Epidermal Growth Factors (EGFs); along with glycerol and rose water.

All these skin-healthy components come together and work to reduce stress lines, reclaim lost moisture and heal damaged skin.

Result? A naturally glowing, revitalized and healthy looking skin without using any harsh chemicals and without any side-effects.

Hex 3 and EGFs are peptides – long chain amino acids – that are making great waves as superior anti-aging ingredients. Peptides signal cells to produce more collagen, repair damaged skin and fight wrinkles and fine lines. They do all that you could ask for to give your skin a new lease of life and make your skin more beautiful.

Epidermal Growth Factors are The ultimate skin rejuvenators

Epidermal growth factor or EGF as it is commonly called is basically a polypeptide – a chain of amino acids. EGFs are naturally occurring proteins known to stimulate cellular growth, healing and regeneration [1].

Growth factors were discovered in 1986 by two scientists, Stanley Cohen and Rita Levi-Motalcini, who received a Nobel Prize in Medicine for this breakthrough discovery. Their work gave revolutionary insights into the ways in which cells communicate with each other during growth, differentiation, repair and healing.

EGFs encourage cellular repair and wound healing in the skin – meaning it possess incredible rejuvenating and age-reversing potential, all tapped and unlocked in our unique SkinFactor cream. When we say skin damage or repair, it includes injury or damage due to sun exposure, pollution, free radicals, burns, surgery and ageing. Basically, it works with unhealthy, damaged skin that needs repair and regeneration.

The skin repair and rejuvenating benefits offered by EGFs shouldn’t be surprising. These growth factors are naturally present in the fibroblasts of our skin, which are the cells responsible for producing extracellular matrix and collagen. A body of randomized controlled clinical trials suggest that topical growth factors achieve similar outcomes as endogenous growth factors, and reduce the signs associated with skin ageing. A recent 2016 article reports that topical growth factors are able to help “due to their capacity to promote dermal fibroblast proliferation and to stimulate extracellular matrix formation” [2].

How EGFs function?

Epidermal growth factors support the skin’s natural regeneration and revitalization process

It all starts with the inflammation stage. Inflammation may sound obnoxious but it is an integral mechanism of how our body responds to any injury, damage or infection. During this stage, our body transitions into an aggressive repair and healing mode by initiating certain events, and the release of EGFs is one of them. EGFs kick start cascading bio-chemical pathways that initiate tissue repair and regeneration in damaged skin cells – by signalling other cells and chemicals to arrive at the site of injury – and leads to:

  • Increased production of collagen and other elastin fibres
  • Growth of new blood vessels to supply nutrient and oxygen rich blood at the site of repair
  • Extracellular matrix deposition and remodelling

What does it mean for your skin? Creams with growth factors help in repairing damaged skin fast, boost collagen formation for increased elasticity, reduces age spots and pigmentation, and improve the skin’s integrity.

What is Hexapeptide -3?

Hexapeptide -3: Prevents the formation of expression lines and wrinkles

Like EGFs, Hexapeptide -3 is also a polypeptide. It is a chain of 6 amino acids and a fragment of SNAP-25, a substrate of Botox. Evidence suggest that hexapeptide-3 can reduce wrinkles by 30%, and within an impressive time frame of only 30 days.

How Hex 3 works: Relaxes facial muscles

We all age with time. Fine lines and wrinkles are a part of this natural ageing process. However, some external factors – such as over exposure to sun, smoking, drinking, stress and an unhealthy lifestyle – can play a major role in making our skin to age faster. There is another factor that contributes big time to this process – repetitive facial expressions.

Expressions like smiling, squinting and frowning make the underlying muscles contract, resulting in folds or creases. When we are young, our skin is more elastic and it has the flexibility to easily spring back into its place. But an ageing skin is no longer this versatile and flexible. Repetitive contractions of the facial muscles eventually pave way for permanent grooves and creases on the face. Well, we are all familiar with these furrows. Call them frown lines, crow’s feet or laugh lines, in the end they are something that we all dread. So how Hex 3 can help?

Hex 3 works by relaxing the facial muscles. Basically, Hex 3 blocks the communication that travels from nerves to muscles asking the muscles to contract. How?

At the neuromuscular junction, a site where a nerve fibre meets a muscle fibre:

  • Nerve cells release certain neurotransmitters (Acetylcholine and others)
  • The released chemicals transmit signals that activate a muscle fibre to contract.
  • These neurotransmitters are secreted with the help of SNARE proteins
  • SNARE proteins help nerves to release the neurotransmitters through a process called exocytosis.

Hexapeptide 3 interferes with the working of SNARE protein complex (it mimics one the proteins in the complex) and disrupts their function. Result? Chemicals that signal the muscle to contract are blocked, muscles don’t contract – thus preventing the formation of expression lines or wrinkles.

SkinFactor also contains glycerol and rose water


Glycerol is great for skincare not for one but many reasons:

  • Acts as a highly effective moisturizer
  • Soothes dry, damaged skin
  • Keeps skin nourished and hydrated
  • Enables young skin cells to mature and develop properly

Pure rose water

Besides imparting a delightful fragrance of fresh roses, pure rose water has a lot of skin benefits to offer:

  • Has anti-inflammatory and antioxidant properties
  • Soothes and cools irritated skin
  • Maintains moisture as well as pH balance in the skin
  • Stops bacterial growth, helps in reducing acne and pimples
  • Improves skin tone

Why should you buy SkinFactor?

Because it is one factor missing in your challenge to maintain a healthy, nourished and glowing skin without any side effects at all!!

What makes SkinFactor a unique antiaging cream? Synergistic combination of Hexapeptide, Epidermal growth factors, glycerol and rose water – a rare blend in any skincare product!

  1. Hexapeptide 3 relaxes facial muscles – to avoid expression wrinkles
  2. EGFs stimulate skin regeneration and repair – for better healing against sun exposure and other damage inflicted to skin
  3. EGFs also boosts collagen production – for a firm, elastic and supple skin
  4. Glycerol and rose water helps in keeping skin hydrated, nourished and overall healthy.
  5. Results as effective as Botox application. The big difference?  No toxic side effects, easy application and affordable



  1. Barrientos S et al. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008 Sep-Oct; 16(5):585-601. doi: 10.1111/j.1524-475X.2008.00410.x.
  2. Frank Dreher. Topical Growth Factors for Skin Rejuvenation. Textbook of Aging Skin. Pp 1-12. April 2016.